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 May 20, 2022

       Nicholas Vita
       Chief Executive Officer
       Columbia Care Inc.
       680 Fifth Ave., 24th Floor
       New York, NY 10019

                                                        Re: Columbia Care Inc.
                                                            Form 10-12G
                                                            Filed May 9, 2022
                                                            File No. 000-56294

       Dear Mr. Vita:

              We have completed our review of your filing. We remind you that
the company and its
       management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding
       any review, comments, action or absence of action by the staff.




 Sincerely,


 Division of Corporation Finance

 Office of Life Sciences
       cc:                                              James Guttman, Esq.